Terazosin, an alpha-adrenergic blocker, is a generic medication commonly marketed under the brand name Hytrin. It can help lower high blood pressure, as well as alleviate symptoms of benign prostatic hyperplasia (BPH), which is an enlarged prostate.It also encourages the prostate and bladder muscles to relax in order to reduce symptoms like difficult or painful urination and urgent or frequent urination.
A study completed in 2008 indicates terazosin controls excessive sweating caused by antidepressant use. In this study, conducted by physician Rajnish Mago of Thomas Jefferson University, this medicine decreased the severity and the amount of time patients were affected by hyperhydrosis.
Terazosin causes the veins and arteries to relax and widen, thus improving blood flow. This makes the meidication an effective treatment for high blood pressure. It also is an effective treatment for benign prostatic hyperplasia (BPH), or enlarged prostate. It relaxes muscles of the prostate and bladder neck.
Men with BPH may experience contrasting symptoms, including urinary hesitancy and urinary urgency. Their symptoms can include dribbling when trying to urinate, weak stream, incomplete bladder emptying and painful urination. Terazosin provides relief for these symptoms.
Terazosin is not a cure for high blood pressure or an enlarged prostate. Patients with hypertension should also follow a diet and exercise plan to treat their condition. Those taking it for BPH may not notice the full effect of the drug until they have followed their treatment plan for four to six weeks. It should not be abruptly discontinued. Doing so will necessitate a gradual dose increase if the patient takes the medicine again.
An initial dose of terazosin should not exceed 1 milligram (mg) to allow the body to adjust to the drug. The doctor may gradually increase the dosage. Patients are encouraged to take a dose at bedtime to reduce the risk of falling due to fainting or dizziness. Usually, it will only be taken once daily. Those who experience stomach upset should take the dose with milk or a snack. 4-Amino-2-chloro-6,7-dimethoxyquinazoline (C10H10ClN3O2,CAS No. 23680-84-4) is an ntermediate of in the production of this drug.
Before using terazosin, patients should disclose their other medical conditions, medications, and supplements to avoid a potential interaction. Women who take this drug for high blood pressure should discuss the potential risks of using it while pregnant. As of 2011, it is unknown whether it passes into breast milk. Those who have liver disease, prostate cancer, or low blood pressure may be unable to use terazosin. This alpha blocker may interact with other high blood pressure medications and other medications for an enlarged prostate.