Alendronate sodium(C4H12NNaO7P2.3(H2O)), also known as alendronic acid, is a drug that is used in the treatment and prevention of the degenerative bone disease osteoporosis in women and men. This medication also is used in the treatment of a bone-weakening condition called Paget’s disease. There is also a very specific way to take the drug as well as important side effects to note.
These drugs work by reducing the rate at which bone material is absorbed from bones. Bone is not a static material; it is in constant turnover, with cells called osteoblasts depositing new bone and cells called osteoclasts absorbing bone. Bisphosphonates reduce bone absorption by causing osteoclasts to die prematurely. This helps prevent loss of bone density caused by osteoporosis and reduces the risk of bone fractures. This medication can help to strengthen the bones in a body. It has Vitamin D that absorbs calcium, which is needed to make bones strong.
Fosamax is the brand name of the most popular alendronate sodium. It is such a popular brand that many people actually refer to it as Fosamax. Possible side effects are the same as alendronate sodium and it is advised that Fosamax not be used by those who have an esophagus disorder, can not stand or sit up for 30 minutes, kidney disease or a low amount of blood calcium.
Like many other medications, it has some specific directions that must be followed when taking the daily dose. First, it must be taken first thing upon waking in the morning, along with a glass of plain water. The second important aspect of taking this medication is that at least 30 minutes must elapse between taking alendronate sodium(CAS No. 121268-17-5) and eating or drinking. This includes taking any other medications, particularly antacids and calcium supplements. Finally, someone who is using this medication should not lie down for at least 30 minutes after taking a dose.
Even when taken correctly, alendronate sodium can cause some unpleasant side effects. The most common side effect for women is abdominal pain. Others include pain in muscle, bone or joint, nausea, dyspepia, constipation, diarrhea, flatulence, headache, acid regurgitation. For men the most common side effect of this medicine is acid regurgitation.